T cells from eosinophilic patients produce interleukin-5 with interleukin-2 stimulation

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T cells from eosinophilic patients produce interleukin-5 with interleukin-2 stimulation.

Anti-murine (m) interleukin-5 (IL-5) antibody was found to inhibit eosinophil (Eo) colony formation stimulated by recombinant human (rh) IL-5, but did not inhibit the production of Eo stimulated by rh IL-3 or granulocyte-macrophage colony-stimulating factor (GM-CSF). Conditioned medium (CM) prepared from eosinophilic patients' T cells with interleukin-2 (IL-2) stimulation (T-IL-2-CM), was found...

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T Cells From Eosinophilic Patients Produce Interleukin - 5 With tnterleukin - 2 Stimulation

Anti-murine (m) interleukin-5 (IL-5) antibody was found to inhibit eosinophil (Eo) colony formation stimulated by recombinant human (rh) IL-5, but did not inhibit the production of Eo stimulated by rh lL-3 or granulocyte-macrophage colony-stimulating factor (GM-CSF). Conditioned medium (CM) prepared from eosinophilic patients’ T cells with interleukin-2 (IL-2) stimulation (T-lL-2-CM), was found...

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Serum Interleukin-17 Evaluation in Patients With Eosinophilic Gastrointestinal Disease

Background: Eosinophilic gastrointestinal disorders or diseases (EGIDs) may result from an abnormal immune-mediated response to food antigens. Activated eosinophils release various mediators with inflammatory properties which may result in tissue and subsequently organ damage. The cytokine milieu of these patients has revealed increased levels of pro-inflammatory cytokines, inc...

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Wrestlers’ immune cells produce higher interleukin-6 and lower interleukin-12 and interleukin-13 in response toin vitro mitogen activation

Objective(s):Although recent investigations have shown chronic inflammation and inflammation-associated diseases might be ameliorated by exercise; little is known about the relation between exercise training with anti/pro-inflammatory cytokines. Materials and Methods: This cross sectional study was conducted to compare interleukin-4 (IL-4), IL-6, IL-10, IL-12, IL-13, interferon gamma (IFN-γ) le...

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Cytotoxic T cells both produce and respond to interleukin 2

Interleukin 2 (IL-2) is a T cell-derived lymphokine that serves as a cofactor for the in vitro response of T lymphocytes to antigen and plays an important role in regulating the growth and/or differentiation of these cells (1, 2). It has been postulated (2, 3) that IL-2 is produced by a discrete regulatory T cell subset, with its effects being exerted on a second, functionally distinct subpopul...

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ژورنال

عنوان ژورنال: Blood

سال: 1989

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v73.7.1809.1809